Melatonin is a hormone that is created by the pineal organ. It assumes a critical part in the control of the resting and waking cycle.

Melatonin also inhibits acid generation in the stomach, as do PPI’s and acid blockers like Ranitidine (Zantac)., and interrupts the natural processes which result in the relaxation of the lower esophageal sphincter (LES) – all good for cutting down on acid reflux.

A 2006 study compared a combination of melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine, with 20 mg omeprazole (a PPI – an often used treatment for the control of acid). All patients using melatonin experienced complete regression in symptoms of acid reflux after 40 days of treatment, compared to the omeprazole group, of which only 66% experienced complete regression.

An endorsement for use in controlling acid reflux found on : “I was trying everything with minimum success until I tried melatonin and it really did the trick!”

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